SOURCE: Journal of the American Medical Association
New Study Reassures Women About The Risks To Their Babies of Taking Antidepressant Drugs in Late Pregnancy
Researchers from Brigham and Women's Hospital in Boston examined medical records of nearly 4 million women diagnosed with depression, who filled a prescription for anti-depressants during the last 90 days of pregnancy. Researchers were most interested in the use of selective serotonin reuptake inhibitor antidepressants (SSRI). The records of pregnant women who did not take an antidepressant were also examined, and the number of babies born with PPHN was compared in each group.
The researchers found that the apparent risk of PPHN in women exposed to SSRI antidepressants returns to normal when accounting for other differences in the women who use the antidepressants. There might still be a very small possibility of harm from the drugs, but far less than the drugs' proven mood benefits. The findings provide pregnant women useful information they can use to talk with their doctors about the balance of benefits and harms from antidepressants when considering their options for treatment.